Syncope and ECG Changes

I was listening to CQI when a case of syncope came up, and the conversation turned to CDU syncope, and it got me thinking about serial ECGs and troponins in ECGs and eventually I started to think about why do we care about ECGs in syncope patients- and then we got to this POTD. So lets get chatting. 


Syncope is defined as a transient loss of consciousness that is self limited and accompanied by transient lose of tone. Approximately 50% of the time when a patient presents to the ED with syncope, there is an etiology determined, 50% of the time it is unclear why a patient syncopizes. Of that 50% of the time the reason is determined it is usually from a detailed history and physical exam, not often found from studies. 


What I wanted to focus on today was the 9.5-18% of the time when syncope is related to a cardiac cause. This is often due to the patient having an underlying cardiac etiology and is associated with a high rate of mortality and an elderly population. 


SO- you are looking at an ECG what should you be looking for in a patient with syncope? I normally am not a mnemonic person but thought this was a helpful one I came across: “ABCDE Left Right” 


A: AV Block: 

  • First start by looking at the PR interval: 

    • PR >200 ms: First Degree heart block, could be causing dizziness and syncope 

  • Notice a pattern between p waves and morphology: 

    • Dropped QRS complex with a normal P wave: Second Degree Mobitz type 1: (Wenckebach) 

    • Dropped QRS with a fixed PR interval: Mobitz type II 

  • Atrial and ventricular dissociation: Third Degree Heart Block


B: Brugada Pattern: 

  • Type 1: Coved pattern in leads V1/V2

  • Type 2: Saddleback appearance in the ST segment in V1/V2

  • Caused by a genetic mutation in the sodium channel of cardiac myocytes

  • Patient will have a family hx of sudden cardiac death


C: QTc Prolongation 

  • QTc is considered prolonged if it measures more than 440 ms in males/460 ms in females 

  • Should be measured from the end of the beginning of the QRS complex to the end of the T wave 

  • Typically measured in lead II or V5/V6 

  • Etiology to include a variety of electrolyte abnormalities: hypoK, hypoMg, hypCa, increased ICP, or medication induced, or genetic (Long QT Syndrome) 

  • In the case of genetic conditions, also consider if the patient has a family hx of sudden cardiac death


D: Delta Waves

  • A classic delta wave: shortened PR interval with slurred QRS upstroke is pathognomonic for Wolff Parkinson White Syndrome (WPW)

  • Caused by an electric conduction along an accessory pathway 

  • Look for these in limb leads and/or precordial leads 


E: Epsilon Waves 

  • Epsilon wave: inflection point between the QRS and the ST segment pathognomonic for arrhythmogenic right ventricular cardiomyopathy (ARVD)

  • Typically seen in leads V1 and/or V2

  • ARVD: is a genetic condition that presents with conduction impairment due to fatty fibrous deposits in the cardiac myocytes 

Left: 

  • Evidence of Left ventricular hypertrophy

  • Could represent any signs for left heart strain including HCOM, aortic stenosis, coarctation, aortic regur, mitral regurg 

  • Huge precordial R and S waves that overlap with adjacent leads 

  • LV strain pattern with ST depression and T wave inversions in I, aVL, and V5-6

Right: 

  • Evidence of right ventricular strain: ST segment depressions and T wave inversions in the right sided leads (V1-V4) and/or inferior limb leads II, III, AVF usually with right axis deviation 

  • Concern for right ventricular strain would be concerning for pulmonary embolism 

    • Must look for SIQ3T3 


TLDR: 

  • Syncope and ECGs, take a look at ABCDE Left Right:

    • AV Block: look at your PR interval and P and QRS morphology

    • Brugada: look at V1/V2 for saddleback deformities

    • QTc Prolongation: more than double the R-R is long! 

    • Delta wave: upswinging QRS in the precordial/limb leads

    • Epsilon wave: inflection at the QRS between ST segment at V1/V2 concerning for ARVD

    • Left heart strain: huge R and S waves

    • R heart strain: signs of strain in the right sided/inferior leads 

https://www.emdocs.net/ecg-pointers-7-cant-miss-ecg-patterns-of-high-risk-syncope-the-abcde-left-right-mnemonic/

https://litfl.com/left-ventricular-hypertrophy-lvh-ecg-library/

https://litfl.com/syncope/


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