Decision Making Capacity

In the 1914 case of Schloendorff versus the Society of New York Hospital, Justice Cardozo wrote, “every human being of adult years and sound mind has a right to determine what shall be done with his own body.” Determining a "sound mind," or decision making capacity is something that we do often in the emergency department. This makes many providers uncomfortable because it gives patients the ability to refuse our recommendations. This POTD is going to go over what defines capacity and how we can assess it. 

Capacity refers to the ability of a person to utilize information about their illness and proposed treatments to make a choice that aligns with their values. Determining capacity is often a clinical judgment typically made by a physician, whereas competence is a legal state determined by a judge. Assessing for capacity allows us to act in our patient’s best interest while respecting their autonomy. 

You can assess for capacity by determining if the patient has the ability to: 1. Communicate 2. Understand the information 3. Understand the situation 4. Manipulate the information presented and make a logical decision.

These points can be ascertained by asking the patient to recount their story, your recommendations, state what they do or don't want, and back their decision up with logic. 

It is important to note that capacity is defined around a specific medical decision; you should assess capacity with each new intervention or treatment proposed. In addition, capacity can be transient and exist along a continuum. So before you call up psych to help determine if your patient can refuse dialysis, go through these 4 points and see if you can determine decision making capacity yourself.

Thanks for reading!

Ariella

References: 

https://www.emrap.org/episode/november2014/decisionmaking

https://www.uptodate.com/contents/assessment-of-decision-making-capacity-in-adults

Ariella Cohen

M.D. Emergency Medicine

Maimonides Medical Center


Olanzapine + Benzodiazepines

Today, I’m going to touch on the co-administration of olanzapine with benzodiazepines.

Data is controversial regarding this, but the co-administration has not been studied in depth, which is why it is not currently recommended to give both. 

What’s the FDA’s stance?

“Concomitant administration of intramuscular olanzapine along with benzodiazepines is not recommended due to the potential for excessive sedation and cardiorespiratory depression.”

This advisory came about after there were 160 adverse events and 29 fatalities associated with IM olanzapine in 2005. 


Possible side effects of co-administration: Severe hypotension, respiratory depression

Why the FDA warning?

There was a study (n=29) looking at patient fatalities involving the administration of olanzapine.

3/29 fatalities involved olanzapine monotherapy.

1/29 fatalities involved IM olanzapine + benzodiazepine dual therapy

25/29 fatalities involved IM olanzapine + PO/IM/IV benzodiazepines + many other medications

The interesting thing about the study is that 12 patients died over 24 hours after administration of the medications. So it’s difficult to determine causality. 

Some olanzapine quick facts:

  • Olanzapine is an atypical antipsychotic

  • Side effect profile includes: neuroleptic malignant syndrome, hyperglycemia, constipation, dry mouth, tachycardia, orthostatic hypotension

    • Mortalities and increased risk of cerebrovascular accidents have been linked to elderly patients with dementia

  • IM olanzapine is 5 times more potent than PO olanzapine. 

  • ½ life: 21-54 hours

  • Peak: within 15-45 minutes

Why is this conversation controversial?

Well, if you look at the data regarding co-administration < 60 minutes apart studied in 41 patients, you see that their vitals are actually fine.

**** 4 Key takeaways ****

  1. According to the European Medicines Agency, it’s likely safe to administer olanzapine and a BZD at least 60 minutes apart

  2. It’s safer to use PO agents over IM agents. Our ED pharmacy team does not recommend administering IM of both

  3. Avoid co-administration particularly in high risk groups: elderly, dementia, acute alcohol intoxication, or patients requiring polypharmacy.

  4. If you’ve already used olanzapine, and you’re looking for an additional agent, ketamine is likely a safer option.

References: 

https://www.aliem.com/combination-parenteral-olanzapine-benzodiazepines-agitation-adverse-events/ 

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125121/ 

https://foamcast.org/2019/10/29/black-boxed-medications-in-the-ed-acep-2019/ 

https://meridian.allenpress.com/mhc/article/8/5/208/37281/Coadministration-of-intramuscular-olanzapine-and 


POTD:  An Uninvited Guest (Wellness Friday)

POTD:  An Uninvited Guest (Wellness Friday)

an uninvited guest

settles in the valley of my heart

makes a home within my chest

and refuses to depart

 

the mountains of my lungs

are crumbling down beneath his weight

as he pollutes the peace once there

with oppression and hate

 

there are waves of emotions

that pound against my veins

lost in a whirl of wind

as they rage in a hurricane

 

the currents get rough

and I find myself lost at sea

within a jagged ocean as vast

as the emptiness I flee

 

my nights have grown longer

as I struggle to fall asleep

my days have blurred together

and my body has grown weak

 

tracks run over my wrist

as the departing train voices its last call

is it better to feel pain

than to feel nothing at all?

 

emotions cloud my thoughts

smoke fogs up my mind

they tell me I’m not good enough

that I’m not worth it to the Divine

 

my faith is shaking

I can’t find who I am

I am enchained by anxiety

as desolation takes command

 

saltwater shakes my core

and spills over the rims of my eyes

as the ocean drowns me

I succumb to numbness inside

 

I frantically glance into the distance

and find His lighthouse shining from miles away

guiding me home

from tides that make me stray

 

He shows me the universe;

constellations trace my skin

and even when I’m breaking,

my galaxies shine from stardust within

 

He shows me the dawn;

as it breaks, so do I

but there’s a beauty in my breaking

as red and gold paint the morning sky

 

To Him I am worth more

than this world entirely

and that’s all I need to overcome

my haunting thoughts of mortality

 

an honorable guest

has settled in the valley of my heart

He illuminates it with hope and light

in places I’ve broken apart

 

-SS Barkat

________________________________

It's World Mental Health Day tomorrow!

One in five adults suffer from a mental illness each year within the United States. More Americans struggle with depression than they do with coronary heart disease, cancer, and HIV/AIDS2. Unfortunately, stigmas founded on misunderstandings of mental illnesses are common. Some may inappropriately label the lack of energy that a depressed individual struggles with as laziness. In turn, those that are suffering turn away from getting the professional help that they need from fear of what people may say.

The “uninvited guest” in this poem refers to depression. The poem’s title aims to demonstrate that depression is just as real as any other physical disease that one may have. It isn’t a state that those suffering choose to be in; rather, depression appears uninvited and begins to govern the mind and body of the victim. Overall, the purpose of this poem is to share the complex nature of depression, the thoughts that may plague the minds of those that are depressed, and ways in which we can all look at the signs around us to remember our self worth in times that we feel lost and hopeless.

By sharing experiences and having open and honest conversations about mental health, we can become a step closer to shattering stigmas and improving access to treatment and services as a community of health care workers.

Have a friend who needs help?; Give them a hug, a pat on the back. Let them cry on your shoulder or your lap. Don't underestimate the power of simple things.

 Ask for help when it gets too much:

National Suicide Hotline: 1-800-273-8255

NYC Well: 1-888-NYC-WELL or Text "WELL" to 65173

In-house: Erica Hutchinson, Ph.D.

Office: (718) 283-8174

Work Cell: (347) 996-6090

 

Have a great weekend and stay well,

TR Adam

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