POTD- Wacky Wednesday! This one brought to you from the curious mind of our very own TINA NGUYEN!!! And why is it wacky? Well because we rarely see it and can hardly say it... today were talking
What is it?
- Alpha virus transmitted by mosquitoes Aedes aegyoti and aedes albopictus
Where is it?
- Endemic to West Africa and Latin America but seen EVERYWHERE!
- Think of it in recent immigrants or travelers
How do you get it?
- Mosquito bite, blood products, organ transplant, maternal fetal ( a/w miscarriage, highest transmission if infected during the intrapartum period)
Symptoms:
- Acute: 1-14 days
- Fever- High grade, lasts 3-5days
- Polyarthralgias- bilateral, symmetric, distal>proximal
- Skin- Nonspecific, 40-75% pts, macpap rash, pruritis
- Complications:
- Resp failure, myocarditis, acute hepatitis, renal failure, CNS involvement, hemorrhage, death
- Prersistent or relapsed disease with arthralgias, tenosynotvitis, raynauds
Workup:
- Labs: Lymphopenia, thrombocytopenia, Elevated transaminases, ^Cr
- Diagnosis: RT-PCR if within 1-7days of onset after ELISA testing
- R/o Dengue and Zika also!
Treatment:
- Supportive care- Rest, fluids, acetaminophen, NSAIDs
- Careful of ASA or NSAIDs until you r/o dengue as they can increase severity of disease
- Immune-compromised- Consider broad spectrum abx and consult ID!!
Sources: CDC, WHO, UpToDate