Want to broaden your differential for hypotension? Do you have a younger patient with hypotension and lab abnormalities? A patient with hypotension refractory to pressers? Think of acute adrenal insufficiency!
I dont have much in the way of additional pearls today - this is pretty self explanatory.
Concerned that your patient ran out of cortisol? Give cortisol (hydrocortisone). You wont diagnose it if you dont suspect it - so keep it on the differential!