Optic nerve sheath diameter (ONSD)
The optic nerve sheath communicates directly with the intracranial space. For the few of us that are not great at the fundoscopic exam, measuring the ONSD might be an easier alternative to evaluate for papilledema (but see test characteristics below).
How to:
Use a linear probe
Use a lot of gel over a closed eye lid
Find the hypoechoic optic nerve and the more echogenic nerve sheath surrounding the nerve
Measure the entire sheath from outer edge to outer edge at a depth of 3mm posterior to the globe (see image above)
Measurements
< 5mm is normal
5 – 6mm is a grey zone
>6mm is abnormal
Evidence
These cutoffs have a sensitivity 88-100%, specificity 63-95% for papilledema (1). The problem is many patients end up in the 'grey zone'.
*A normal ONSD does not necessarily indicate normal intracranial pressure (ICP). A dilated ONSD might also be normal for that patient, so correlate clinically!
**ONSD unfortunately can't be used to estimate a specific ICP.
So the next time you find yourself wanting to do a fundoscopic exam, whip out your probe instead! (or use the new retinal camera in fast track...)
Back to the patient
Neurology was consulted, the patient was started on acetazolamide, and admitted to medicine. Interestingly, her CSF VZV PCR was positive so she was diagnosed with VZV meningitis. She was started on antivirals and did well overall. Her vision problems and headaches improved.
References:
Shevlin, C. (2015). Optic nerve sheath ultrasound for the bedside diagnosis of intracranial hypertension: pitfalls and potential. Critical Care Horizons, 1(1), 22-30.
Farkas, J. (2017). PulmCrit: Algorithm for diagnosing ICP elevation with ocular sonography. (https://emcrit.org/pulmcrit/pulmcrit-algorithm-diagnosing-icp-elevation-ocular-sonography/)
This is my last post as your ultrasound education fellow 😢. If you've read this far, I appreciate you! Thanks Dr. Danta for coming up with most of my titles ha ha ha... Dr. Ariella Cohen will take us thru the home stretch!! 🙌