How to Hook up Multiple Patients to the Same Vent

Today, we’re going to talk about hooking up multiple intubated patients to the same ventilator.  As the coronavirus becomes increasingly more prevalent and more patients require intubation, knowing how to do this may become more important than ever before.

 

  • Why would I do this?

    • As more and more patients require intubation, ventilators are going to become a precious resource.  We want to maximize our resources to help as many people as possible.

    • So what are the downsides?

    • You can no longer adjust the vent to optimize it for a single patient

      • Under normal circumstances, you want to optimize vent settings for a specific patient

      • This allows you to maximize oxygenation and ventilation while also keeping the patient as comfortable as possible on the ventilator in order to avoid having to over-sedate the patient

    • You can no longer allow a patient to trigger the vent

      • Under normal circumstances, vents allow a patient to trigger a breath

        • This is helpful because it is more comfortable for the patient and will allow an intubated patient to be less sedated

      • However, you don’t want one patient triggering breaths on the vent and thereby affecting every other patient

        • For example, if one patient is tachypneic and triggering breaths, all other patients attached to the same vent will be forced to breathe at this rate as well

    • Ventilation is less effective

      • In order to attach multiple patients to a single vent, you will need to use a large amount of tubing with Y-site connectors

      • This results in increased dead space making tidal volumes less accurate

      • As a result, patients are more likely to develop hypercapnia in this setup

        • This will likely require permissive hypercapnia in these patients

  • Now that we understand the downsides to this setup, let’s discuss the settings you will need to consider

    • You will want to use pressure control for these patients

      • Why not volume control?

        • Normally, volume control is helpful because it allows you to provide a specific tidal volume to a patient, but is limited because it allows no control over peak pressure

        • When you have multiple patients attached to a single vent, however, you are no longer able to accurately control the tidal volume of any single patient

        • If there is a problem with one patient, for example if there is an obstruction or kinking of the ET tube, than the other patient on the vent will get significantly increased tidal volume as the volume intended for 2 patients enters only 1.  This can result in dangerously high peak pressures and barotrauma.

        • If you want to hook up multiple patients to the same vent with volume control, they would all need to receive the same volume, meaning they should all be a similar size.  This further restricts which patients may be placed on the same vent.

      • Why is pressure control better?

        • Even with multiple patients hooked up to the same vent, you can maintain adequate control over the peak pressures supplied.

        • If there is a problem with one patient, for example there is an obstruction or kinking of one ET tube, it will not affect the other patient.  The patient with the problematic ET tube will receive less tidal volume, but the other patient on the vent will be unaffected.

        • Different sized patients can be hooked up to the same vent, since larger patients have higher compliance and therefore will receive larger breaths

    • You should set the vent to continuous mandatory ventilation

      • You do not want patients to trigger the vent and thereby affect other patients attached

      • Instead, you need continuous mandatory ventilation, in which the vent is set to a fixed rate and the patient cannot trigger the vent

      • If the vent does not have this mode as an option, you can instead max out the ventilator trigger threshold, thereby preventing patients from triggering the vent

        • If this doesn’t work or the patient is fighting the vent, then you may need to consider sedation that also suppresses the respiratory drive such as opiates and propofol

        • If even that is unsuccessful and the patient is still fighting or triggering the vent, you may need to consider paralytics

  • Ok, now we understand the pros and cons, as well as the settings we need. How do we set this up?

    • First, make sure the patients you are attaching to a single ventilator have similar vent requirements; ie don’t attach a patient who needs an FiO2 of 30% and PEEP of 5 to the same machine as a patient who needs an FiO2 of 100% and PEEP of 15

    • Set up the vent settings as discussed above

    • Attach viral filters to prevent cross-contamination between patients

    • Using Y-site connectors, attach the expiratory and inspiratory limbs of the vent to all ET tubes as shown in the diagram

  • Keep in mind, that this setup has been tested primarily with lung models and animals; there isn’t significant data from human studies.  But it may be important despite this going forward!

Pics courtesy of emcrit.org 

Stay safe everyone!

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ARDS

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Acute respiratory distress syndrome (ARDS) 

acute inflammatory lung injury that causes non-cardiogenic pulmonary edema by increasing alveolar capillary permeability. 

The thickened diffusion barrier leads to hypoxemia via:

decreased lung compliance

inefficient gas exchange

Pulmonary hypertension

increased physiological dead space

Predisposing factors:

Direct lung injury: pneumonia, gastric aspiration, pulmonary contusion, near drowning, inhalation injury, transfusion-related acute lung injury

Indirect lung injury: sepsis, shock, acute pancreatitis, burns, crush injury, fat embolism, and massive transfusion

Diagnosis criteria for ARDS – Berlin definition (all 4 components must be present):

  1. Acute onset (1 week or less)

  2. Hypoxemia (PF ratio* < 200 mmHg with a minimum of 5 cmH2O PEEP (or CPAP))

  3. Pulmonary edema (bilateral opacities on CXR)

  4. Non-cardiogenic (not caused by cardiac failure)

*PF (PaO2/FiO2) ratio is the ratio of arterial oxygen partial pressure to fractional inspired oxygen. PaO2 value can be obtained from ABG, and FiO2 is 0.21 at sea level (room air) or depends on supplemental O2.

 

ARDS is a diagnosis of exclusion so consider first: 

Cardiogenic pulmonary edema, severe multilobar pneumonia, acute exacerbation of pulmonary fibrosis, diffuse alveolar hemorrhage, idiopathic acute eosinophilic pneumonia, dissemination of lymphoma/leukemia, and several others. 

 

Workup:

Labs: CBC, BMP, LFTs, Coags, VBG followed by ABG, troponin, BNP, lipase, consider DD

Imaging: CXR, POCUS US ECHO and CHEST and consider CT

 

 

ED Management:

Supplemental O2

Treat the underlying condition (pneumonia, sepsis, etc.)

Tempered diuresis – non-cardiogenic pulmonary edema takes much longer to respond to treatment than cardiogenic CHF, so avoid being overly aggressive with diuresis, as this may worsen underlying shock and increase likelihood of multi-organ failure

Glucocorticoids — consider steroids when ARDS precipitated by a steroid-responsive process (eg, acute eosinophilic pneumonia)

Be cautious when using non-invasive positive pressure ventilation – the benefit of NIPPV in the initial management of ARDS remains controversial. 

Mostlikely patient will end up being intubated, for vent management suggested strategies are:

Use low tidal volume (6-8 mL/kg) to avoid barotrauma (ideal body weight should be calculated)

And careful FiO2:PEEP ratio titration:

 

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ARDS severity (mortality) predictor 

Mild ARDS – The PaO2/FiO2 is >200 mmHg, but ≤300 mmHg, on ventilator settings that include positive end-expiratory pressure (PEEP) or continuous positive airway pressure (CPAP) ≥5 cm H2O

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Moderate ARDS – The PaO2/FiO2 is >100 mmHg, but ≤200 mmHg, on ventilator settings that include PEEP ≥5 cm H2O

Severe ARDS – The PaO2/FiO2 is ≤100 mmHg on ventilator settings that include PEEP ≥5 cm H2O.